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VU 0357121
CAS No. 433967-28-3
VU 0357121 ( VU-0357121, VU0357121, VU 0357121 )
产品货号. M18548 CAS No. 433967-28-3
VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥437 | 有现货 |
|
| 10MG | ￥705 | 有现货 |
|
| 25MG | ￥1499 | 有现货 |
|
| 50MG | ￥2989 | 有现货 |
|
| 100MG | ￥4496 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称VU 0357121
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.
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产品描述VU0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that VU0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site.
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同义词VU-0357121, VU0357121, VU 0357121
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通路Others
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靶点Other Targets
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受体mGluR5
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number433967-28-3
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分子量305.32
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分子式C17H17F2NO2
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纯度98%
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溶解度DMSO : ≥ 50 mg/mL; 163.76 mM
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SMILESCCCCOc1ccc(cc1)C(=O)Nc1c(cc(cc1)F)F
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化学全称4-Butoxy-N-(2,4-difluorophenyl)benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Hammond AS, et al. ACS Chem Neurosci, 2010, 1(10), 702-716.
产品手册
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